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Abstract

In today’s world, there is a pressing need for environmentally friendly drugs of natural origin, with high bioavailability, no side effects or addiction, for immune reconstitution and enhancement, in particular, after viral or bacterial infections, and for prevention of diseases. It is expected that new drugs derived from the bursa of Fabricius of broiler chickens, one of which is Bursanatal, will aim to influence the damaged part of the immune system caused by various diseases, of both viral and bacterial etiology, and to restore the damaged part of the immune system, since Bursanatal contains essential and non-essential amino acids, vitamins, micronutrients, which beneficially contribute to the restoration of the human body after an infection, and by immune enhancement, they facilitate prevention of several diseases.

In this study, an attempt was made to develop biostimulating substances and obtain a number of drugs, one of which is Bursanatal based on extraction from the bursa of Fabricius of broiler chickens. The study aims to characterize the new immunomodulatory drug Bursanatal and identify its biostimulating and bioenhancing potential. An analysis of the physicochemical properties of Bursanatal showed that due to its unique composition and several components, such as proteins with a molecular weight between 10.0 and 1 kDa, amino acids, macro- and micronutrients, water-soluble and fat-soluble vitamins, Bursanatal has various biological properties, including immunomodulatory, immunostimulating, apoptogenic, anti-inflammatory, antiviral and metabolism-correcting effects‎.

Keywords: Bursanatal, Tissue preparation, Bursa of Fabricius, Immune enhancement, Immune modulation, Physicochemical properties

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