Study of long-term outcomes of cholecystectomy at cholelithiasis
Abstract
Currently, publications on the stage-by-stage progression of complications of cholecystocholedocholithiasis suggest that after cholecystectomy, the gastrointestinal tract also undergoes stage-by-stage disorders. It is these causal relationships about changes in the gastrointestinal tract after cholecystectomy that remain insufficiently studied. Therefore, this study aimed to improve the results of treatment of cholelithiasis complications in the postoperative period. 65 patients previously operated on for cholelithiasis (group A) were examined. For comparison, a group of patients who did not undergo cholecystectomy (group B) was taken - 54 people. Group A is divided into two subgroups, taking into account the duration of the long-term postoperative period: up to 1 year and after 3 years. Then the frequency of clinical signs and fibrogastroduodenoscopy data were compared with histological examination of the esophageal mucosa, stomach, and duodenum. When comparing the subgroups, it was found that with an increase in the duration of the long-term postoperative period, the pain syndrome changes, and some dyspeptic disorders increase. The consequence of cholecystectomy is changes in the morphological structure of the stomach and duodenum, which are manifested by mucosal erosions and reflux gastritis, which worsen the quality of life of patients in the long-term postoperative period.
Keywords: Cholelithiasis, Cholecystectomy, H. pylori, Fibrogastroduodenoscopy
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