TY - JOUR T1 - Study of long-term outcomes of cholecystectomy at cholelithiasis A1 - Ahmed Aslanov A1 - Rustam Kalibatov A1 - Oksana Logvina A1 - Murat Gotyzhev A1 - Liana Kardanova A1 - Zalim Bakov A1 - Zalim Baksanokov A1 - Liza Taukenova A1 - Artur Zhirikov JF - Journal of Advanced Pharmacy Education and Research JO - J Adv Pharm Educ Res SN - 2249-3379 Y1 - 2024 VL - 14 IS - 4 DO - 10.51847/McqjHWYZDG SP - 76 EP - 81 N2 - Currently, publications on the stage-by-stage progression of complications of cholecystocholedocholithiasis suggest that after cholecystectomy, the gastrointestinal tract also undergoes stage-by-stage disorders. It is these causal relationships about changes in the gastrointestinal tract after cholecystectomy that remain insufficiently studied. Therefore, this study aimed to improve the results of treatment of cholelithiasis complications in the postoperative period. 65 patients previously operated on for cholelithiasis (group A) were examined. For comparison, a group of patients who did not undergo cholecystectomy (group B) was taken - 54 people. Group A is divided into two subgroups, taking into account the duration of the long-term postoperative period: up to 1 year and after 3 years. Then the frequency of clinical signs and fibrogastroduodenoscopy data were compared with histological examination of the esophageal mucosa, stomach, and duodenum. When comparing the subgroups, it was found that with an increase in the duration of the long-term postoperative period, the pain syndrome changes, and some dyspeptic disorders increase. The consequence of cholecystectomy is changes in the morphological structure of the stomach and duodenum, which are manifested by mucosal erosions and reflux gastritis, which worsen the quality of life of patients in the long-term postoperative period‎. UR - https://japer.in/article/study-of-long-term-outcomes-of-cholecystectomy-at-cholelithiasis-42fwy47sbi1bujt ER -