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Abstract

This study evaluated the effectiveness of the Semangat application in improving antiretroviral treatment (ART) adherence, eHealth literacy (EHL), and human immunodeficiency virus (HIV)-related knowledge among people living with HIV in Indonesia. A quasi-experimental study was conducted among 494 PLWH in 20 primary health centers in Jakarta, equally assigned to an intervention group (IG) and a control group (CG). The IG used the Semangat app for 4 weeks, while the CG received standard care. Outcomes were assessed before and after the intervention using self-administered questionnaires. Baseline characteristics and outcomes were comparable. After the intervention, high adherence increased to 70% in the IG, compared with just over 50% in the CG (p < 0.001). EHL improved markedly in the IG (22.77 to 24.79), with 61.1% achieving good EHL, compared with 30.8% in the CG. HIV knowledge gains were also significantly higher in the IG (p < 0.001). Nearly half rated the app’s usability as good/very good, and 60% were satisfied. In conclusion, Semangat improves ART adherence, EHL, and HIV knowledge, supporting its value as a complement to standard HIV care.

Keywords: Electronic health literacy, HIV, Knowledge, Medication adherence

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