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Abstract

The expanding chemical production, particularly from the pharmaceutical industry, has led to the generation of significant wastes and pollutants, prompting the need for a comparative assessment of efficiency across various chemical manufacturing sectors. Green chemistry has emerged as a holistic approach, aiming to minimize the adverse impacts on human health and the environment by devising innovative chemical processes that tackle pollution at its source. The application of green chemistry principles within the pharmaceutical industry has focused on the development of eco-friendly solvents, catalysts, and manufacturing processes while acknowledging the challenges posed by the complexity of pharmaceutical molecules and stringent regulatory requirements. This paper emphasizes the significance of green chemistry practices, such as microwave-assisted organic synthesis and UV/H₂O₂ treatment for the removal of pharmaceuticals from liquid waste, highlighting their contributions to reducing waste and energy expenses. Moreover, the implementation of Quality by Design (QbD) principles in pharmaceutical development has resulted in improved product performance and reduced product variability, ensuring the highest standards of safety and quality. With a specific emphasis on solvent recovery and reduction, the paper underscores the critical role of these strategies in curbing emissions and fostering sustainable practices within the pharmaceutical industry‎.

Keywords: Green chemistry, Pollution, Pharmaceutical plants, Implementation, Microwave synthesis

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