Pul-Luzan Viktoriia , Oliinyk Svitlana , Yarnykh Tatyana , Rukhmakova Olga , Dankevych Oksana

Abstract

The purpose of this review article is to give an overview of the relevance of the use of glucocorticosteroids in veterinary medicines for the treatment of various pathologies in animals, namely cats and dogs. Glucocorticosteroids (GCS) are one of the most commonly used drugs in veterinary medicine, they are powerful anti-inflammatory, and immunosuppressive agents. Corticosteroids are effective in dogs and cats with various diseases: allergic reactions of various etiologies, diseases of the urinary system, ear diseases, various dermatitis. Localglucocorticosteroids (topical corticosteroids (T GCS)) are the main and virtually uncontested drugs for the external treatment of many dermatoses. Due to its anti-inflammatory, antipruritic, immunomodulatory effects, local GCS are the drugs of choice for several diseases in humans and animals. Recently, veterinarians shave identified several skin diseases, the treatment of which is based on drugs with GCS. This group of diseases is called steroid-sensitive dermatoses. It includes diseases that differ in pathogenesis and clinical manifestations, but they are united by the need for a suppressive effect on the cells of the immune system associated with the skin. These are atopic dermatitis (AD), allergic dermatitis, and many others. Modern synthetic corticosteroids have a greater affinity for glucocorticoid receptors, and therefore the effect develops much faster and lasts longer. The article presents glucocorticosteroids, which are most often used in veterinary practice. Two classifications of glucocorticosteroid activity and principles of dosing are presented‎.

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