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Supplement for controlling blood lipids and maintaining anthropometric indicators in obese women: Zinc or Lactobacillus casei


, , ,
  1. Department of Pharmacy, Health Polytechnic Makassar, Makassar, Indonesia.
  2. Department of Nutrition, Health Polytechnic Makassar, Makassar, Indonesia.
  3. Academy Pharmacy of Yamasi, Makassar, Indonesia.

Abstract

Dietary plans, pharmaceutical therapies, physical activity, and psychological approaches are some of the methods that have been suggested to address weight excess and its negative effects. Food supplements that are now on the market have several claimed modes of action, including enhanced energy expenditure or lipolysis, improved glucose metabolism, and decreased appetite. Based on previous studies, it seems reasonable to assume that Probiotic and Zn supplementation may have favorable effects on weight loss or reversing obesity-related comorbidities. Therefore, this study was designed to compare the effects of daily intake of 30 mg Zinc (Zn) supplement and 6,5x109 CFU/day Lactobacillus casei (LCS) as Probiotic along with RCD on anthropometric measurements and lipid profiles in obese individuals. For 30 days, 84 participants were randomly assigned to one of four groups: zinc (30 mg/day), LCS (6,5x109 CFU/day), "zinc and LCS," or placebo. Anthropometric markers, food intake, stress levels, physical activity, and lipid profiles were assessed before and after the intervention. After controlling by confounding variable, in this study was dietary intake, the greatest reduction in total cholesterol levels was in the Zn group. The largest increase in HDL-C levels was in the Zn+LCS group. The largest decrease in LDL-C levels was in the combined Zn+LCS group. The greatest reduction in triglyceride levels was in the Zn group. The largest decrease in waist circumference was found in the Zn group. Likewise, the largest decrease in percent body fat after was in the Zn group.



Keywords: Supplement, Blood lipid profiles, Anthropometric indicators, Obese, Zinc, Lactobacillus casei


How to cite this article:
Vancouver
Rusli R, Hartono R, Andini M, Djajanti AD. Supplement for controlling blood lipids and maintaining anthropometric indicators in obese women: Zinc or Lactobacillus casei. J Adv Pharm Educ Res. 2025;15(1):35-42. https://doi.org/10.51847/Q7QvXU3iyN
APA
Rusli, R., Hartono, R., Andini, M., & Djajanti, A. D. (2025). Supplement for controlling blood lipids and maintaining anthropometric indicators in obese women: Zinc or Lactobacillus casei. Journal of Advanced Pharmacy Education and Research, 15(1), 35-42. https://doi.org/10.51847/Q7QvXU3iyN
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