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Abstract

Improving transfusion safety is a major challenge in medicine, requiring rigorous, diversified training for all those involved in the transfusion chain. Objective: This study aims to evaluate the impact of using simulation-based serious games, in particular a fun card game, on medical students' learning of ABO and RHD compatibility principles, with a focus on their ability to retain and apply this crucial knowledge. A total of 260 health students, who had previously attended a lecture course on transfusion compatibility, took part in this study. An educational card game was introduced to reinforce the concepts covered. Students' performance was measured using pre- and post-tests, guaranteeing participants' anonymity. In addition, a satisfaction questionnaire was distributed to assess student acceptance of this fun learning method. Among the 260 participants, the results showed a significant improvement in knowledge, with the mean score rising from 8.12 ± 3.9 before the intervention to 15.89 after the game (p=0.0001). The majority of students found the approach simple, engaging and enjoyable, which boosted their motivation and involvement. This study demonstrates that the integration of low-cost, interactive simulation-based serious games can not only boost learners' motivation but also significantly improve their mastery of blood transfusion concepts, making learning more structured and memorable‎.

Keywords: ABO, Blood transfusion, Compatibility, Medical students, RHD, Serious game

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