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Abstract

The present study determines the pattern of albumin consumption in liver transplant patients hospitalized in Masih Daneshvari Hospital. This retrospective study examined the data of 39 patients who received albumin in the liver transplant department of Masih Daneshvari Hospital.

SOFA and APACHE scores were used as primary outcomes to examine the relationship with albumin consumption and qualitative parameters including the need for abdominal reoperation, the occurrence of ascites, the occurrence of thrombosis, the receipt of PC and FFP, the rejection of the transplant, and the death or survival of the patients one and three months after transplantation as secondary outcomes. The occurrence of pleural effusion, hemodialysis, and CRRT were also collected by extracting them from the patient's medical records. The mean albumin consumption in g/kg of the patient's body weight was calculated to be 2.43 ± 1.39 g/kg in the patients of this study. This value in vials was also calculated to be 19.02 ± 10.87 vials per patient. The mean albumin level of the patients was also calculated up to one week after transplantation, which was 3.3 ± 1.58 g/dl.  In contrast, the mean and standard deviation of the plasma albumin level was 3.05 ± 2.21 g/dl before surgery. Based on the results, albumin consumption cannot have a significant impact on improving the APACHE score index. The present study revealed that implementing a drug consumption assessment program for albumin can optimize the duration of drug administration and significantly reduce the number of inappropriate doses‎.

Keywords: Albumin, Liver transplant, Hypoalbuminemia, consumption