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Abstract

This research delves into the antimicrobial potential of aqueous extracts from six distinct plant species against clinically relevant bacterial pathogens. Hibiscus sabdariffa exhibits efficacy against Streptococcus faecalis, Staphylococcus aureus, and Klebsiella sp., positioning it as a promising natural antimicrobial agent. Trigonella filipes and Trigonella strangulata display significant zones of inhibition against Citrobacter sp., Escherichia coli, and Pseudomonas aeruginosa, underscoring their potential as sources of potent antimicrobial compounds. The study reveals variations in Minimal Inhibitory Concentration (MIC) values among the plant extracts, emphasizing their diverse antimicrobial profiles. Allium sativum (garlic) and Medicago sativa exhibit the lowest MIC of 4 µl against Staphylococcus aureus, highlighting their efficacy, while Trigonella strangulata requires the highest MIC of 50 µl. The research methodology, including the extraction process, bacterial cultures, and evaluation techniques such as the cup diffusion and MIC determination methods, is detailed. These findings provide valuable insights into the antimicrobial potential of six plant extracts, encouraging further exploration of their mechanisms and therapeutic applications in addressing bacterial infections. Keywords: Plant extracts, Antimicrobial activity, Minimal Inhibitory Concentration (MIC), Clinical pathogens, Natural remedies‎.