Nutritional status in patients with COPD and its impact on biochemical status: A narrative review
Abstract
A progressive respiratory disease marked by continuous airflow restriction and major systemic repercussions including nutritional imbalances, COPD is Disease progression, mortality rates, healthcare expenses, hospital stays, readmissions, muscular strength, and respiratory muscle function all are greatly influenced by nutrition and biochemical indicators. Common in COPD patients, malnutrition—especially protein-energy shortage and micronutrient insufficiency—contributes to muscle atrophy, lowered immunity, systemic inflammation, and poor pulmonary function. The purpose of this narrative review is to investigate in COPD how dietary status and biochemical indicators interact to influence disease outcomes. The review was conducted using PubMed, MEDLINE, and Scopus databases, employing keywords such as COPD, nutritional status, biochemical markers, malnutrition, and disease outcomes. Important results show how dietary deficits—such as low levels of vitamins (D, C, E) and minerals (magnesium, zinc)—cause changed metabolic parameters that contribute to oxidative stress and inflammation. On the other hand, dietary changes and supplements are part of nutritional therapies that show promise to enhance clinical and functional results. Dealing with the interaction between illness outcomes, biochemical indicators, and nutritional status emphasizes for COPD sufferers the need for integrated treatment plans. Standardized criteria for nutritional evaluation and treatments to maximize illness management require further study.
Keywords: COPD, Nutritional status, Biochemical markers, Malnutrition, Disease outcomes
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