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Abstract

This retrospective study included data from 39 patients who received albumin in the liver transplantation department of Masih Daneshvari Hospital. The samples of this study were collected from the entire study population in the days before surgery until one week after liver transplantation surgery. SOFA and APACHE scores were used as primary outcomes to find their association with the level of albumin consumption and qualitative parameters including the need for abdominal reoperation, the occurrence of ascites, the occurrence of thrombosis, receiving or non-receiving PC and FFP, the transplant rejection, and the death or survival of the patients one and three months after transplantation as secondary outcomes. The occurrence of pleural effusion, the occurrence of hemodialysis, and the occurrence of CRRT were also collected by extracting data from patients’ medical records. Statistical correlation analyses revealed that albumin consumption is significantly associated with the SOFA score (p-value = 0.025 and correlation coefficient = 0.358), but it did not show a significant relationship with the APACHE Score (p-value = 0.097 and correlation coefficient = 0.296). It was found that the level of injected albumin per kilogram of body weight was significantly correlated with the SOFA score on the third day. This means that with the change in the level of injected albumin per kilogram of body weight, the changes in the SOFA score on the third day were also significant.

Keywords: Liver disease, Albumin, Patient weight, APACHE score, SOFA score