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Abstract

The current research progress on (psoriatic arthritis) PsA pathogenesis has clarified the crucial role of early diagnosis and treatment in disease development and quality of life (QoL). Demographic information, clinical and paraclinical information, and PsA severity were documented. The patients were followed up for one year. The data were collected using the Health Assessment Questionnaire (HAQ), developed under the auspices of the Stanford Arthritis, Rheumatism, and Aging Medical Information System, and The Disease Activity Score-28 (DAS-28) was calculated. Data were analyzed by SPSS25 statistical software and the Spearman correlation coefficient test. Fifty patients (62% women) with a mean PsA duration of 11.7 years were enrolled. The most frequent type of PsA was symmetric polyarthritis (48%), followed by asymmetric oligoarticular (30%). The mean uveitis, dactylitis, enthesis, Nail involvement, and swollen/tender joint counts were 24%, 22%, 28%, 56%, and 78%, respectively. Nearly half of patients (56%) had metabolic syndrome. 30(60%) patients were treated with methotrexate.

 There was a high correlation between Skin disease severity and swollen/tender joint counts. There were no significant differences between smoking or alcohol consumption with Disease Activity in Psoriatic Arthritis. In addition, there was no significant statistical difference between Disease Activity in Psoriatic Arthritis and a positive family history of psoriasis in our patients. This study is designed to evaluate Psoriatic arthritis types and determine comorbidities patterns, treatment regimes, and disease characteristics in PsA patients treated at Imam Khomeini Hospital.