A Systematic Review of the Comparative Efficacy of Allografts and Xenografts in Alveolar Bone Defect Reconstruction
Abstract
The dimensions of the alveolar ridge are becoming increasingly significant due to the greater trend towards implant rehabilitation. Ridge augmentation involves the use of bone transplants to encourage bone regrowth. Although autogenous bone grafts taken from patients are thought to be the gold standard, they can cause postoperative pain and increase the risk of infection at the donor site. Therefore, there is a need for alternative materials, including the use of allogeneic and xenogeneic transplants. Considering the importance of regenerating alveolar bone defects and the variety of bone graft sources, along with the diverse studies examining the effects of each graft type, The present research compares the efficacy of xenografts and allografts in the regeneration of alveolar bone lesions using a systematic review methodology.
Without limiting the start date, a thorough literature search was conducted until September 2024. Guidelines for meta-analyses and Preferred Reporting Items for Systematic Reviews were followed while choosing articles. Included were five researches. There was one retrospective analysis and four randomized clinical trials. No statistically significant difference between the two treatment methods was found in the majority of the investigations. Both allografts and xenografts are effective in the reconstruction of alveolar bone defects. Studies involving larger sample sizes and more extensive augmentation procedures are recommended.
Keywords: Alveolar bone loss, Allografts, Xenografts, Osteogenesis, Dental implant
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