Regulation of drug transmission within the matrices of different polymers and the models of drug delivery
The polymers are applied widely in the preparation of controlled release dosage forms. The model of drug release provides important information about the mechanism of their effect on drug release and clarifying the method of drug transmission within the tablets in comparison with its macroscopic appearance. The article will discuss the structure, charge, physicochemical properties, and concentration of polymer on the rate and the mechanism of drug release. The properties of the drug, the dissolution medium, and the other ingredients and their effect on drug release will be discussed. Moreover, the article will provide information about their uses in pharmacy and medicine. The article's goal is to focus on the effects of mixing different polymers with drugs and other ingredients on the preparation of controlled release dosage forms and to elucidate the drug release mechanism.
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