Abstract

Purpose and the basis: The purpose of this study is the effects of 8 weeks resistance and endurance training on the myostatin and follistatin serum levels in postmenopausal women. Materials and Methods: The subjects were 30 menopausal women randomly divided in one of the four groups aged as groups of endurance (55.33±2.75), resistance (50±3.11), control (53±2.16). Training program was conducted in 3 sessions for 8 week. The endurance training program included a 45-minute walk on a treadmill with severity of MHR (Maximum Heart Rate) of 40-65%. The resistance training program included some exercises selected from upper and lower extremities, with a severity of 1RM (1 Repeat Major) of 40-65%) which were done in 45 minutes. Two blood samples were taken 24hours before the first session and 48 hours after the last session of the subjects. To compare the data of all 3 groups we used a one way ANOVA test. Results: The result showed a significant difference between 3 groups in myostatin (p =0.036) and follistatin (p =0.008). After post hoc comparisons a significant decrease was found in myostatin serum in resistance exercise group compared to endurance exercise and control groups (respectively, p =0.048 and p =0.004). Also significant increase observed in resistance and endurance exercise groups (respectively, p =0.002 and p =0.009). Conclusion: Because endurance training just increased follistatin and resistance training increased follistatin and on the other hand decreased myostatin. Therefore, resistance training seems to be a more effective intervention for improving the metabolic status of postmenopausal women.