Abstract

Cholesterol rich diets become more favorable nowadays, may be because of it makes food tastier but in long term, fatty diets possess fatty liver and chronic kidney disease leading to more series status like Diabetes and Heart disease if not controlled by healthy strategies like switching to salubrious diets. Ancient peoples have benefits from extraction of Teminali arjuna as antioxidant and anti-hypercholesterolemia agent. The data inquiry provides the liver and kidney protective roles of Terminalia arjuna ethanolic extract in chow (5% cholesterol+0.5% cholic acid) induced hyperlipidemia rats. The liver and renal function tests assess by using Biolabo kit/France and the excremental rats designed into 3 groups (Control, hyperlipidemia rats and T.arjuna treated hyperlipidemia rats). In The current inquiry, Rats fed on chow had significantly higher values of (SGOT, SGPT, serum creatinine, ALP and Blood urea) and the values of (S.albumine, S.globuline and total protein) cutback significantly in compare to control rat groups. the biomarkers of renal function and hepatocellular activity in induced hyperlipidemia rats significantly affected by abating T.arjuna extract in their diet. Notably, the level of Uric acid, blood sugar and amylase enzyme significantly cutback in induced hyperlipidemia rats treated with extract of T.arjuna bark. Terminalia arjuna bark extract (500 mg/kg body weight) could be used as active antilipidemia and efficient liver and kidney protective agents in obese patients or long term fatty diet consumers. As shown to have positive feedback on hepatic and renal functions and become able to cut off high levels of Uric acid, blood urea and amylase enzyme in induced hyperlipidemia rats.