Research on the treatment of settling sediments in the production process of Ich mau extracts
Abstract
In Vietnam, Ich mau (Leonurus japonicus Houtt, Lamiaceae) is curently used as a medicine to regulate menstruation and treat dysmenorrhea. This research will determine the parameters of the time to settle the liquid extract and the amount of settling liquid S obtained in each production batch to contribute to the completion of the production process on an industrial scale. Medicinal herbs will be collected in different seasons of the year, meeting the standards of Vietnam's Pharmacopoeia V. Excipients included ethanol, sugar, and benzoic acid. Prepare Ich mau extracts medicine according to the formula of Vietnam’s Pharmacopoeia with the volume of 1 packing unit is 100 ml. Evaluation of the quality of Ich mau extracts according to the standards of Vietnam’s Pharmacopoeia V. The batches of preparation with or without the use of liquid S all obtained the products that met the requirements of testing criteria. Ich mau extracts meet the requirements of the test criteria after 3, 6, 9, and 12 months of storage. With raw materials from different regions and seasons, the project has researched to standardize the technical parameters of the production process such as: settling time t, the volume of clear liquid T, volume of settling liquid S. We will continue to monitor the product's long-term stability to prolong the life of the medicine.
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