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Relationship between TIMI myocardial perfusion grade and ST resolution in evaluating the coronary reperfusion


Reza Faramrza Zadeh , Venous Shahabi Rabori

Abstract

The current research was conducted and implemented to evaluate the relationship between TIMI grade and STR after PCI. By reviewing the medical record of 112 patients with diagnosis of acute coronary syndrome and under coronary angiography, the primary characteristics of the patients were extracted in this research. Coronary flow was evaluated after PCI by 200 μg nitroglycerin bolus intracoronary prescribing. TIMI value was determined based on the contrast opacification dynamics of coronary microcirculation. By aggregating the total values in increase in ST in all infarction leads and reduction in reciprocal leads, SSTD value was determined. Relative SSTD value, which means percentage of reduction in SSTD (SSTD%) compared to its base value, was calculated. Strong and significant correlation was found between TIMI variations after PCI and SSTD (correlation coefficient=0.340, P = 0.001). Additionally, a strong and significant correlation was found between TIMI variations after PCI and SSTD% (correlation coefficient =0.442, P = 0.001). Based on the analysis of area under the ROC curve, evaluation of SSTD (AUC = 0.699) and SSTD% (AUC = 0.621) could predict improvement in TIMI flow in patients after PCI. According to the analysis of area under ROC curve, evaluation of SSTD (AUC = 0.667) and SSTD% (AUC = 0.873) could predict the occurrence of mortality in patients after PCI. Measuring STR can predict TIMI grade variations strongly after performing the PCI process. In addition, determining STR has great value in predicting the mortality after the mentioned procedure.




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