Sweta Gautam, Yogesh Shivhare

Abstract

The study of free radicals and antioxidants in biology is producing medical revolution that promises a new age of health and disease management. The present study was performed to evaluate antioxidant effect of petroleum ether and methanolic extract of Praecitrullus fistulosus against free radical damage by standard method as DPPH (1,1- diphenyl-2-picrylhydrazyl) free radical model. Results indicate that fruits possess varying degree of antioxidant activity when compared with standard ascorbic acid. The IC50 of pet-ether extract is 182g/ml and ethanol extract is 202g/ml.