Shahnooshi Javad F

Abstract

Charcot arthropathy (Charcot neuroarthropathy, diabetic neuropathic osteoarthropathy, or neuropathic arthropathy) remains a poorly understood disease. The etiology of Charcot remains unknown, although it has been suggested that it is triggered by the occurrence of inflammation in the foot of a susceptible individual, and that the inflammation results in increased osteoclastic activity, although recent research has improved our level of knowledge regarding its management. It has been well established that this complication of diabetes mellitus severely reduces the overall quality of life and dramatically increases the morbidity and mortality of patients. The goal of this study is to evaluate the modern concepts of Charcot arthropathy and to integrate a perspective of management.