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Investigation of the association between serum HbA1c level and hemodynamic variables in diabetic patients undergoing prostatectomy


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Abstract

HbA1c is one of the most important predictors of complications in diabetic patients.  present study aimed to investigate the association between the HbA1c level and hemodynamic variation during general anesthesia. 100 prostatectomy candidates patientes with type 2 diabetes were included in the study from 2018 to 2019 in two groups: (A) HbA1c < 6.5 and (B) HbA1c ≥ 6.5 . systolic and diastolic blood pressures, mean arterial pressure, and heart rate was measured before and 10 minutes and 60 minute after induction of anesthesia and compared between two groups. results were analyzed by Student‘s t-test and (ANOVA). The mean age of patients were the same in two groups ( 63.22 vs 63.78 years). No significant difference was found between the two groups in terms of mean BMI at a 95% confidence level. The mean BMI was 36.79 for Group A and 35.60 for Group B (P-V = 0.065). There was no significant difference between the two groups in terms of the duration of diabetes. The mean duration of diabetes for Groups A and B was 3.86 and 3.64 years, respectively (P = 0.522). The ANOVA results show that the mean variables of systolic pressure, diastolic pressure, MAP, heart rate, and blood glucose for patients of Group B, compared to Group A, changed significantly in the measured times (P-V>0.05). In patients with HbA1c below 6.5, hemodynamic variables are more stable during general anesthesia for prostatectomy.


How to cite this article:
Vancouver
Morshedizadeh Z, Ahmadipour M, Mahani SM. Investigation of the association between serum HbA1c level and hemodynamic variables in diabetic patients undergoing prostatectomy. J Adv Pharm Educ Res. 2022;12(4):91-6. https://doi.org/10.51847/siaJR24mvL
APA
Morshedizadeh, Z., Ahmadipour, M., & Mahani, S. M. (2022). Investigation of the association between serum HbA1c level and hemodynamic variables in diabetic patients undergoing prostatectomy. Journal of Advanced Pharmacy Education and Research, 12(4), 91-96. https://doi.org/10.51847/siaJR24mvL
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