Heba A Mousa Galeb, Hala M Ezzeldin, Samah M. Ismail, Soheir ‎Abdel Fatah Abo Elfadl, Hossam M Elkady‎

Abstract

Background: It was found that blood pressure, p-selectin, and ICAM -1 reduced and six-minute walk distance increased by concurrent training in hypertension, but research covering this area in blood group A is limited. Objective: The current study aimed to evaluate the efficacy of exercise training program on p-selectin and ICAM -1 in hypertensive patients with blood group A. Patients and methods: The study was performed on twenty patients from both sexes with the age ranged from 40 to 55 years who performed concurrent training for ~45–60 min per session involving 20–40 min of aerobic and 15–40 min of resistance exercise, 3 session per week for 10 weeks in addition to their traditional medications. Blood pressure, p-selectin, ICAM-1, and six-minute walk distance were measured before and after the study. Results: Statistical analysis revealed that the blood group A positively responded to concurrent training by decreasing systolic, diastolic, p-selectin, and ICAM-1 by 9.54%, 11.34%, 42.42%, and 36.03%, respectively and increasing six-minute walk distance by 24.83%. Conclusion: It was recommended to hypertensive patients with blood group A to practice concurrent training to decrease the risk of cardiovascular complications‎.