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Hala Salim Sonbol , Salman Bakr Hosawi , Maram Bakr Hosawi

Abstract

Capparis cartilaginea (C. cartilaginea) is a plant with various bioactivities found in the Kingdom of Saudi Arabia. It has the biological and chemical properties of medicinal plants, used traditionally for the treatment of many diseases. Bioactive phytochemicals that are present in medicinal plants are promising alternatives to improve the treatment efficacy of human diseases. In developed countries, prostate cancer (PCa) is the most common cancer in males. Various therapies have been proposed for cancer treatment, many of which use products derived from plants. The active compounds of C. cartilaginea were found in nearly all plants of the Capparidaceae family, such as alkaloids, tannins, saponins, steroids, terpenoids, flavonoids, phlobatannins, phenolic constituents, glycosides. This study aimed to screen the bioactive phytochemicals compounds and anticancer activity of C. cartilaginea fruit extract. Gas chromatography-mass spectrometry (GC-MS) analysis was used to highlight the major components of the C. cartilaginea fruit extracts. The GC chromatogram profile determined the existence of six main peaks, and the related components were known to be 2-Furancarboxaldehyde, 5-methyl-; 4H-Pyran-4-one, 2,3-dihydro-3,5-dihydroxy-6-methyl-; 5-Hydroxymethylfurfural; Hexadecanoic acid, ethyl ester; 9-Octadecenamide, (Z)-; and 13-Docosenamide, (Z)-. Our research is novel and the results obtained suggested the possible use of the ethanol extract of C. cartilaginea fruit as a medicinal plant for preparing an anticancer treatment‎.

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