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Evaluation of Cardiac function changes in children with Bronchiectasis admitted to Mofid Children's Hospital


Ghamartaj Khanbabaee1, Mohammad Nanbakhsh2*, Mohammadreza Khalilian3, Roxana Azma4, Nazanin Farahbakhsh and et al

Abstract

Background: Bronchiectasis is a chronic respiratory disease which occurs as a consequence of inflammation and destruction of the structural components of the bronchial wall. This study was aimed to determine of cardiac function changes in children with bronchiectasis admitted to Mofid Children's hospital, Tehran, Iran. Methods: In this study, 30 patients with bronchiectasis were enrolled in this study and their identification data, weight and height were recorded in the data collection form. Modified Reiff Score was measured. The patients were referred to the pediatric cardiologic clinic and echocardiography was performed by a pediatric cardiologist at the resting state in supine or left-lateral position and compared them with 30 healthy age- and gender-matched control subjects. All data was entered and analyzed using SPSS version 21. Results: The mean age was 12.0 years and 17 patients (57%) were males. The severity of the disease was in 10 patients (33%) mild, 18 cases (60%) moderate and 2 cases (7%) severe based on clinical score. The mean score of the Modified Reiff Score was 8.4±3.5. The value of RVMPI and LVMPI in patients with bronchiectasis was higher compared with the control group. There was a positive correlation between the Modified Reiff Score and the clinical score (r = 0.719, P <0.001), which is highly significant indicating the increase of clinical status along with Modified Reiff score. Conclusions: According to the findings, it can conclude that increasing the Modified Reiff Score can be a good predictor of the clinical status of patients with bronchiectasis.



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