Abstract

Introduction: patients with renal insufficiency have Considerable number of emergency room admissions. The route ‎and dose of most drugs should be adjusted based on patients renal function, this study tried to evaluate ‎antibiotic dose maladjustment in emergency unit of academic hospital.‎ Method‎: 120 Patients who were admmitted because of different types of infections and have been treated by ‎antibiotic in emergency department investigated in this Study. GFR of patients have been Calculated ‎and dose of antibiotic that should be adjusted based on GER were evaluated. Results‎: Most common types of infections have been treated in emergency department were Pulmonary, urinary ‎tract and central nervous system infection, most common antibiotics that have been used in emergency ‎were ciprofloxacin, Vancomycin, imipenem  and ceftriaxone . 67% dose maladjustment were seen that ‎mostly were by use of ciprofloxacin, vancomycin and imipenem.‎ Conclusion: Antibiotics dose maladjustment is so common in emergency department and most common ‎inappropriate dose of antibiotics were most common that have been used in emergency‎‎‎‎‎‎‎‎‎.