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Evaluation of Analgesic Activity of Different Leaf Extracts of Celastrus paniculatus (willd.)

Monojit Debnath1, Moulisha Biswas, K. Nishteswar


Celastrus paniculatus Willd. (Celastraceae), commonly known as Staff tree in English, is a woody climber grown in tropics and subtropics and also cultivated commercially in India for the high demand of its seed oil. The present study assessed the different solvent extracts of C. paniculatus leaf for the evaluation of their analgesic potential by acetic acid induced writhing assay in Swiss albino mice. All of test extracts exhibited significant analgesic activity. The methanol extract was found to be the most potent followed by the ethyl acetate and petroleum ether extracts respectively. The present preliminary study demonstrates marked analgesic activity of C. paniculatus leaf.

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