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Evaluation of acute anti-inflammatory activity of Psidium guajava leaf extracts in Wistar albino rats

Esita Bera , Sanjib Bhattacharya , Moulisha Biswas


Psidium guajava L. (Myrtaceae), commonly known as guava in English, is an evergreen small tree grown in tropics and subtropics and also cultivated commercially in India for its consumable fruits. The present study assessed two defatted successive solvent (ethyl acetate and methanol) extracts of P. guajava leaf for their acute anti-inflammatory potential by carrageenan induced hind paw oedema in Wistar albino rats. Both the test extracts exhibited significant and comparable anti-inflammatory activity. The methanol extract was found to be a bit more active than the ethyl acetate extract. The present preliminary study demonstrated promising acute anti-inflammatory activity of P. guajava leaf in Wistar rats.

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