Abstract

Background: Diagnosis of coronary artery disease (CAD) is one of the important aspects of management and treatment of these patients. The purpose of this study was to evaluate the diagnostic accuracy of Blood Oxygen Level Dependent (BOLD) cardiovascular magnetic resonance (CMR) in coronary artery disease compared with invasive angiography. Methods: A total of 20 patients with suspected CAD were enrolled. All patients were subjected to invasive angiography using standard and conventional methods. BOLD CMR was performed in 3 short axis slices of the heart at rest and during adenosine stress (140 μg/ kg / min) followed by late gadolinium enhancement (LGE) imaging (2mmol / kg gadolinium). Results: In this study 20 patients were studied in 11 (55%) males and 9 (45%) females with an average age of 59.34 ± 5.43 years. 16 (80%) pationts were diagnosed with coronary artery disease. The mean and standard deviation of delta t2 in patients with an abnormal angiogram (-3.49 ± 4.40) are higher than those with normal angiogram (2.83 ± 0.17). However, these changes were significant between the two groups (p = 0.006). The BOLD imaging diagnostic power for coronary artery disease was shown to be 0.788 (standard deviation 0.57-0.100) for the delta t2 variable. Conclusion: The results of this study indicate that BOLD imaging can be a non-invasive technique suitable for diagnosing CAD compared with invasive methods.