‎Tabatabaei RS., Azizi R., Hajisafar Tafti M., Namiranian N., Javaheri A., Ghadiri-Anari ‎A., Dehghan N.‎

Abstract

The aim of this study is Comparison of pregnancy outcomes in high risk pregnant women with ‎normal FBS after OGTT test in first trimester of pregnancy and 24-28 weeks of pregnancy. ‎This was a follow up study on pregnant mothers who were at risk of developing gestational ‎diabetes at the beginning of the first trimester of pregnancy. Patients were divided to 2 ‎groups: 164 women had a 2-hour OGTT test with 75 g glucose in the first trimester and 251 ‎ones had -hour OGTT test with 75 g glucose in the second trimester. The studied populations ‎were monitored during the entire pregnancy period in term of complications of gestational ‎diabetes. All of this information was recorded and analyzed by SPSS 19. Based on results, ‎there is no significant difference between two groups in term of these risk factors. The ‎frequency of gestational diabetes mellitus in the first trimester was significantly more than ‎the second trimester (p value = 0.001). In the population with GDM, there was no significant ‎difference between maternal and fetal complications in the two groups. The prevalence of ‎preeclampsia, macrosomia, cesarean section related to gestational diabetes, fetal ‎complications were not significant between two groups. There was a significant difference ‎between the two groups in terms rate of insulin therapy (p-value = 0.035), but there was no ‎significant difference between the two groups in term of other pharmacological and non-‎pharmacological treatment. Due to the lack of significant difference in some of the ‎complications of gestational diabetes (preeclampsia, cesarean section associated with GDM) ‎and fetal complications between the two groups, it can be concluded that early screening ‎before 24 weeks in women with risk factors for gestational diabetes leads to more costs and ‎discomfort for pregnant mothers without any So, screening for each patient should be done ‎individually in accordance with an accurate assessment of his pregnancy and risk factors for ‎diabetes‎‎‎‎‎‎‎‎‎‎‎‎.