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Comparative analysis of the efficacy of Paracetamol and Naproxen as a preemptive analgesia following surgical dental extraction



Abstract

Compare the efficacy of Naproxen and Paracetamol as preemptive analgesia following ‎‎surgical tooth extraction.A randomized, double-blind, parallel, study was conducted in a private dental clinic. The ‎‎participants signed a free and informed consent form. All participants (n = 40; both genders; ‎‎‎20–29 years old) were indicated for extraction of a tooth. Patients with chronic illnesses, ‎‎allergic to drugs used in the study, pregnant or lactating participants, smoker or patients used ‎‎analgesia one week before the surgery were excluded. All the 40 participants were randomized ‎‎into two groups (Group A and Group B), each group having 20 participants. They double-blindly ‎‎received single oral doses of naproxen mg or paracetamol 1 gm 60 min before the extraction, and the doses were packed in an envelope and coded by numbers for later identification

Forty participants were randomly selected for the study. Participants who were given Naproxen have shown a higher analgesic effect compared to Paracetamol (1000 mg). Participants that took the first rescue analgesic dose after 3 hours are more in the Paracetamol group. While those who took the first rescue analgesia dose at 5 hours are more in the Naproxen group. In the dental clinics, teeth extraction has become a routine procedure, which associated with moderate to severe pain, preemptive administration of analgesic medication has been found to greatly reduce post-operative pain.


How to cite this article:
Vancouver
‎Mohammed MA. Comparative analysis of the efficacy of Paracetamol and Naproxen as a preemptive analgesia following surgical dental extraction. J Adv Pharm Educ Res. 2021;11(1):178-81. https://doi.org/10.51847/2I6C9exBYN
APA
‎Mohammed, M. A. (2021). Comparative analysis of the efficacy of Paracetamol and Naproxen as a preemptive analgesia following surgical dental extraction. Journal of Advanced Pharmacy Education and Research, 11(1), 178-181. https://doi.org/10.51847/2I6C9exBYN
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