A.Tamil Selvan, B. Jayalaxmi, R. PAshvini, R.Suthakaran, Vishwanath

Abstract

Medicinal plants have curative properties due to the presence of various complex chemical substance of different composition which are found as secondary metabolites in one or more parts of these plants. Triphala Karpa Chooranam a traditional medicine used for curing kidney stones contains Terminalia chebula, Phyllanthus emblica, Terminalia bellerica, Karungali sathu and Vengai sathu. Preclinical evaluation of the herbal formulation shows significant antiurolithiatic action against ethylene glycol and calcium oxalate induced urolithiasis in rat model. The histopathology of the kidney section shows no damaged cells of formulation treated and Cystone treated (750mg/kg) compared with that of the control animals. The urine analysis showed reduction in the excretion of oxalate crystals in both test and the standard treated groups.