× Copyright Disclaimer Privacy Policy Author Guidelines Current Issue Archive Publishing Ethics Join As Reviewer Advertise Submit Article Abstracting And Indexing Editorial Board Contact Editor-in-Chief Scope of the Journal About the Journal


JAPER is indexed in SCOPUS

Antipyretic activity of Pterolobium hexapetalum (Roth.) Sant. and Wagh. Stem bark extracts


B. Kavitha, N. Yasodamma, E. Sreenivasulu Reddy

Abstract

Pterolobium hexapetalum (Caesalpiniaceae) is one of the important herbal medicines against chest pain, fever, cough, tooth ache, dog bite, diarrhoea, ulcer, jaundice, skin disorders, constipation, piles and venereal diseases. Also possess high quantities of phytoconstituents in leaf, stem bark, flower and fruit extracts like flavonoides, alkaloids, phenols, glycosides, saponins steroids, tannins and quinines. P. hexapetalum extracts also proved as effective antimicrobial, antiulcerous, antidiarrhoel and antioxidant herbal drug through in – vitro and in – vivo studies. P. hexapetalum stem bark extracts have been evaluated for their antipyretic activity against yeast – induced pyrexia in rats. The methanol as well as water extracts of the stem bark showed potential antipyretic activity. It was observed that methanol extract at a dose of 400 mg/kg body weight significantly elevated body temperature of rabbit showed maximum antipyretic activity than water extract. The effect produced was comparable with the standard antipyretic drug paracetamol. Hence present investigation reveals the antipyretic activities of the methanolic and water extracts of the stem bark extracts of P. hexapetalum.




Contact SPER Publications


SPER Publications and Solutions Pvt. Ltd.

HD - 236,
Near The Shri Ram Millenium School,
Sector 135,
Noida-Greater Noida Expressway,
Noida-201301 [Delhi-NCR] India