Bodhisattwa Chakraborty, Uttam Kumar Bhattacharyya, Rana Datta1, Manik Boral, Bibek Laha, Subhangkar Nandy

Abstract

To evaluate the anti-inflammatory and anti-asthmatic property with their phytoconstituents of the methanolic extracts of Alangium lamarkii leaves. Alangium lamarkii (Family-Alangiaceae) commonly known as Ankora is found in western Africa, Madagascar, southern and eastern Asia. It is mainly used traditionally for inflammations, blood disorders, burning sensation, spermatorrhoea, gleet, acute fever and lumbago. In the present study, methanolic extract of Alangium lamarkii was evaluated for anti-inflammatory and anti-asthmatic property with their phytoconstituents using carrageenan induced rat paw oedema and histamine induced bronchoconstriction respectively. Student’s t-test and Dennett’s test were used for statistical analysis. The result showed the presence of alkaloid and steroids in the leaves and significant anti-inflammatory and anti-asthmatic property of methanolic extract of Alangium lamarkii. The methanolic extract of Alangium lamarkii leavesshowed potent anti-inflammatory and anti-asthmatic activity in comparison with the standard drugs diclofenac sodium and Pheniramine Maleate respectively, possibly due to may be presence of alkaloids and steroids in the leaves.