Ahmad Enhesari , Manouchehr Khatami , Mohammad Hossein Gozashti , Zohreh Safi , Mehrdad Khatami

Abstract

Levels of serum uric acid are associated with cardiovascular attacks and high blood pressure. Some researchers have suggested that the serum levels of uric acid may also be related to the thickness of the Intima-mediated carotid. The aim of this study was to evaluate the serum level of uric acid and its relationship with the thickness of Intima-mediated carotid in patients referred to Be’sat Clinic of Kerman. 180 patients, including 86 males and 94 females with an average age of 41.1 ± 3, were studied. In all patients, blood pressure and BMI were measured. Serum levels of uric acid, TG, cholesterol, HDL, LDL, and also the thickness of Intima-mediated carotid was measured and statistically analyzed.

The results of this study showed that the thickness of Intima-mediated carotid significantly correlated with serum uric acid (p = 0.02, r = 0.71). The results also showed that uric acid levels were related with higher BMI and higher levels of metabolic factors. The results of our study generally show that people with higher serum uric acid have a significantly higher thickness of the Intima-mediated carotid. People with high blood pressure also had higher carotid thickness compared to those with normal blood pressure. Other metabolic factors were higher in people with high serum uric acid than those that have levels of normal uric acid‎.

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