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Pharmacopaine aspects of extemporaneous technology of soft medicines and suppositories

Melnik G. M., Yarnykh T. G., Rukhmakova O. A.


It is known that the preparation of extemporaneous medicines is strictly regulated by the provisions of Good Pharmacy Practice (GPP). Particular attention in the rules of GPP is given to ensuring the quality of dosage forms manufactured in pharmacies. In Ukraine, pharmacopoeial requirements for extemporaneous soft medicines and suppositories are set forth in the general pharmacopoeial articles of State Pharmacopoeia of Ukraine of the 2nd edition (volume 3).  In this article, the authors present an analysis of the pharmacopoeia requirements for the indicated dosage forms, which showed that many pharmacopeias of developed countries have common pharmacopeia articles on soft medicines and suppositories. The requirements for these dosage forms are largely similar and do not have significant differences‎.

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