Maha Akram Al-Rejaboo, Anfal Muayad Jalaluldeen

Abstract

The purpose  of this research was to determine the antifungal activity of sage plant (Salvia officinalis L.) alcoholic extract at varying concentrations (5, 10, 15 and 20 mg/ml) against a group of airborne  fungus in vitro as a natural fungicide, which were isolated from indoor and chambers of Mosel University (Alternaria, Acremonium, Aspergillus, Cladosporium, Drechslera, Fusarium, Nigrospora sphaerica, Penicillium, Rhizopus , Stemphylium, Tetreacoccosporium , Yeast). Most of the fungi found in most rooms belonged to the genus, Aspergillus, Penicillium,Cladosporium and Alternaria. These fungus have been considered to be harmful fungi for humans, as they can cause allergies, dyspepsia, eye infections, skin injuries, and chronic bronchitis, elc. The minimum inhibitory concentrations of alcoholic extract  against Alternaria alternata, Aspergillus niger and  penicillium sp were 88, 76, 88% at the concentration of  20mg/ml compared with antifungal Ketoconazol which were  100%,73% and 92% for the fungi Alternaria alternata, Aspergillus niger and penicillium sp; respectively at the concentration of 1.5 mg/ml. Based on the current results, alcoholic extract of Salvia officinalis exhibited  good antifungal activity, and can potentially be a natural replacement of synthetic fungicides to   control a number of significant fungal diseases‎‎.