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Anticancer activity of ethanol extract of Asystasia travancorica Bedd (Acanthaceae) whole plant against Dalton Ascites Lymphoma


Komalavalli.T , Packia Lincy. M , Muthukumarasamy. S Mohan V.R

Abstract

The present study aims to evaluate the antitumor activity of ethanol extract of whole plant of Asystasia travancorica Bedd on DAL induced tumor in Swiss Albino mice. Evaluation of the antitumor effect of ethanol extract of whole plant of Asystasia travancorica on tumor growth and host survival time was made by the study of the following parameters: tumor volume, viable and non viable cell count and life span of host. The results showed decrease in tumor volume and viable cell count. Hematological studies revealed that, the Hb count decreased in DAL treated mice, whereas it was induced by the drug treated animals and showed an increase in Hb near to normal levels. The results suggested that the extract of whole plant of Asystasia travancorica exhibited significant antitumor activity on DAL bearing mice.



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