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Anti-diabetic activity of cassia fistula (alpha amylase – inhibitory effect)


Hena Mariam Fathima , Lakshmi Thangavelu , Anitha Roy

Abstract

Aim: To evaluate the anti-diabetic activity of cassia fistula. Materials and methods: Cassia fistula extract used in the study here was obtained from Green Chem Herbal extracts and formulations, Bengaluru, India. DMEM, FBS, and Pioglitazone, were obtained from Sigma Aldridge co India. Acarbose, dinitrosalicylic acid, DMSO is obtained from Sigma Aldrich co. India. Alpha amylase enzymes were procured from Himedia, Mumbai. All the roger chemicals used in the study were up to analytical grade. The study was carried out as an in vitro study by the method of Bernfeld. Results: cassia fistula showed high alpha amylase inhibitory activity. Conclusion: It can be concluded that cassia fistula shows high alpha amylase inhibitory activity and can be used as medication for diabetes.



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