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Journal of Advanced Pharmacy Education and Research

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Synthesis and Characterization of 2'-chlorospiro [cyclohexane/cyclopentane/cyclo butane-1, 5'-pyrrolo [2,3-d] pyrimidin]-6'(7'H)-one

L.K. Ravindranath K. Sudhakar Babu V. Prabhakar J. Latha

Abstract

A Novel and efficient synthetic sequence for the preparation of 3, 3 di substituted oxi indoles was developed from Pyrimidine hydrazines and α-branched aldehydes via Fisher Indole synthesis followed by imine oxidation.




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