%0 Journal Article
%T Study of the subacute toxicity of a fungicide on rabbits  (Batna region)
%A Taguig Assia
%A Boubsil Soumaya
%A Abdennour Chérif
%A Boulakoud Mohamed Salah
%J Journal of Advanced Pharmacy Education and Research
%@ 2249-3379
%D 2020
%V 10
%N 2
%P 104-109
%X The present study relates to the evaluation of the subacute toxicity of a pesticide widely used in agriculture in the Batna region on a few parameters related to liver and thyroid functions in domestic rabbits. Our experimental study was performed on 12 mature male rabbits of the genus Cuniculus lepus, which were divided into 2 groups (n = 6): a control group (G1) and a treated group (G2) with Rivanebe®80 orally for 15 days. Analysis of the results obtained has shown that treatment with Rivanebe®80 causes harmful effects on the organism, resulting in a significant increase in body mass and consumption of food by treated animals, compared to the control group. In addition, a hepatotoxic effect by a significant increase in the mass of liver and biochemical parameters was reported including hyperglycemia, hypertriglyceridemia, hypercholesterolemia, and an increase in bilirubin and transaminases. Finally, a disturbance of the thyroid function or a significant decrease of the thyroxin plasma levels was also reported.
%U https://japer.in/article/study-of-the-subacute-toxicity-of-a-fungicide-on-rabbits-batna-region