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Preliminary in vitro assessment of anti-inflammatory property of Mikania scandens flower extract


Sangita Chandra , Protapaditya Dey , Sanjib Bhattacharya

Abstract

The present experiment was conducted to assess the anti-inflammatory property of hydroalcoholic extract of the flowers from Mikania scandens against the denaturation of protein in vitro. The test extract at different concentrations was incubated with egg albumin under controlled experimental conditions and subjected to determination of absorbance to evaluate the anti-inflammatory property. Diclofenac sodium was used as the reference drug. The present results exhibited a concentration dependent inhibition of protein (albumin) denaturation by the test extract. The effect of diclofenac sodium was found to be less when compared with the test extract. Form the present findings it can be concluded that the M. scandens flower possessed marked anti-inflammatory effect against the denaturation of protein in vitro.



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