Swati Mohanty, Sindhu Ramesh

Abstract

Periapical inflammatory lesion is the response of bone around the apex of tooth that occurs ‎after the necrosis of the pulp tissue or due to some peri-radicular diseases. Regeneration is the ‎reproduction of a lost or an injured part of the body in such a way that the architecture and ‎function of the lost or injured tissues are completely restored. Bone graft allows faster ‎regeneration and remodeling of osseous defects. PRF, on the other hand is a 2nd generation ‎platelet rich growth factor that acts both as a scaffold and as center for release of various ‎growth factors that further improves bone healing.  This case report, shows the bone ‎regeneration ability of combined use of platelet rich fibrin (PRF) and bio-resorbable ‎Demineralized Bone Matrix (DMBM) – Osseo graft in the treatment of a large periapical ‎lesion‎.