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In vitro antifungal activity of Artabotrys crassifolius Hook.f. & Thomson against clinical isolates of Candida species


Kok Kwan Tan , Teng Jin Khoo , Christophe Wiart

Abstract

The aim of the current study was to examine the antifungal activities of crude extracts of Artabotrys crassifolius on the growth of clinical isolates. The leaves and barks of Artabotrys crassifolius were extracted sequentially with hexane, chloroform and ethanol. The corresponding crude extracts obtained were then subjected to Kirby-Bauer disc diffusion assay. Among the extracts tested, hexane extract of barks demonstrated prominent inhibitory activity which warrants further isolation and characterisation of the bioactive compounds present in the respective extracts.



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