× About the Journal Scope of the Journal Contact Editor-in-Chief Editorial Board Current Issue Archives Abstracting And Indexing Submit Article Advertise Join As Reviewer Publishing Ethics


JAPER is indexed in SCOPUS

In vitro anthelmintic activity of roots of capparis zeylanica linn


Ravindra D. Bendgude , Manish S. Kondawar , Sandeep B. Patil , Rupali V.Hirave

Abstract

Helminth infections are among the most common infections in man; in developing countries they pose a large threat to public. These infections can affect most population in endemic areas with major economic and social consequences. The Capparis zeylanica Linn is commonly known as ‘Indian caper’. The all parts of plant being used from the period of Susruta as acrid, anthelmintic, analgesic, antipyretic, antimicrobial, immunomodulatory effect. The present study was undertaken to evaluate anthelmintic activity of different extracts of roots Capparis zeylanica Linn. [Cappardiaceae] The different successive extracts namely petroleum ether, ethanol and aqueous using Pheretima posthuma as test worms. The different concentrations (0.1%, 0.2% and 0.5%) of various extracts were tested in the bioassay which involved determination of the time of paralysis (P) and time of death (D) of the worms. Albendazole was included as standard reference and normal saline as control. The results of present study indicated that the crude ethanolic extract and aqueous extracts significantly demonstrated paralysis and also caused death of worms in dose dependent manner, as compared to standard reference albendazole. While petroleum ether extract shows weak anthelmintic effect further studies are in process to isolate the active principles responsible for the activity.



DOWNLOAD


Contact SPER Publications


SPER Publications and Solutions Pvt. Ltd.

HD - 236,
Near The Shri Ram Millenium School,
Sector 135,
Noida-Greater Noida Expressway,
Noida-201301 [Delhi-NCR] India