TY - JOUR T1 - Enhanced antibacterial activity of Ciprofloxacin ocular inserts against S. aureus and P. Aeruginosa A1 - Samar Z. Alshawwa JF - Journal of Advanced Pharmacy Education and Research JO - J Adv Pharm Educ Res SN - 2249-3379 Y1 - 2020 VL - 10 IS - 4 SP - 132 EP - 134 N2 - Background: Ciprofloxacin hydrochloride is a common antibiotic used for treating bacterial infections, and enhancing its antibacterial activity is considered a crucial concern of scientific researchers. Objectives:  The objective of this work aim to show the enhancement of the antibacterial activity of ciprofloxacin ocular inserts against P. aeruginosa and S. aureus. Method: The enhancement of antibacterial activity of ciprofloxacin ocular inserts against P. aeruginosa and S. aureus  was evaluated using microbiological susceptibility tests. The inserts composed of two types of spray-dried matrices, SD1 and SD2. Results: Promising results were obtained and the two formulae were found to be effective against S. aureus and P. aeruginosa, also the results indicated clear zones of inhibition every day up to seven days. Conclusion: It was concluded that ciprofloxacin hydrochloride is a good antibacterial agent. UR - https://japer.in/article/enhanced-antibacterial-activity-of-ciprofloxacin-ocular-inserts-against-s-aureus-and-p-aeruginosa ER -