TY  - JOUR
T1  - The effect of formulation and process variables on prepared etoricoxib ‎Nanosponges
A1  - Ahmed Hamed Salman
A1  - Fatima Jalal Al-Gawhari
A1  - Khalid Kadima Al-kinani
JF  - Journal of Advanced Pharmacy Education and Research
JO  - J Adv Pharm Educ Res
SN  - 2249-3379
Y1  - 2021
VL  - 11
IS  - 2
DO  - 10.51847/Q0QRKUV2kQ
SP  - 82
EP  - 87
N2  - To assess the improvement in solubility and drug release using Nanosponges (NS) deliver system. ETX loaded NSs (ETX-NS) were prepared using the emulsion solvent diffusion ‎method. The ratio of drug: polymer (1:0.25,1:1.5: 1:2 and 1:3) for formulas F1, F2, F3, and ‎F4 respectively, the type and quantity of organic solvent used in the preparation, stirring ‎rate, and sonication effects on the solubility, particle size, and entrapment efficiency and ‎entrapment efficiency of prepared NS were investigated and evaluated.

The solubility of ETX was enhanced when formulated as EXT-Ns. The increase in ‎EC proportion in EXT: EC ratio caused a decrease in solubility of prepared EXT-NS ‎‎(p
UR  - https://japer.in/article/the-effect-of-formulation-and-process-variables-on-prepared-etoricoxib-nanosponges-gyljur8ieoukddk
ER  -