TY  - JOUR
T1  - The clinical picture of the damage to the organs of the hepatobiliopancreatic area in hypothyroidism
A1  - Eduard Gukasovich Sarkisyan
A1  - Polina Andreevna Korzhova
A1  - Ruslan Kazbekovich Esiev
A1  - Maria Georgievna Taralova
A1  - Ekaterina Sergeevna Gerasimova
A1  - Egor Anatolyevich Ermakov
A1  - Evdokia Yanisovna Alikhanova
A1  - Robert Alibekovich Botashev
JF  - Journal of Advanced Pharmacy Education and Research
JO  - J Adv Pharm Educ Res
SN  - 2249-3379
Y1  - 2023
VL  - 13
IS  - 4
DO  - 10.51847/iWlul3UmLX
SP  - 30
EP  - 35
N2  - Hypothyroidism is a clinical syndrome caused by hypofunction of the thyroid gland and characterized by a decrease in the content of thyroid hormones in the blood serum. Clinical manifestations of hypothyroidism can be diverse and depend on its etiology, the age of the patient, as well as the rate of development of thyroid hormone deficiency. The disease may have a pronounced clinical picture or, conversely, have no clinical manifestations and be detected randomly. Moreover, the signs of hypothyroidism very often mimic (mask) another pathology. Therefore, the diagnosis of hypothyroidism in some cases is difficult. In this work, a systematic analysis of the literature and clinical studies was carried out, and the negative effect of hypothyroidism in a patient on the liver, biliary system and pancreas was established. When analyzing the effect of hypothyroidism on the liver, no changes were observed in the organ itself. However, serum enzymes increased, such as aspartate aminotransferase, lactate dehydrogenase, and creatine phosphokinase. Violation of lipid metabolism in the liver with hypothyroidism can lead to obesity, which is never significant. Hypothyroidism revealed a violation of the biliary system and the development of cholelithiasis. There is a scientific study on the relationship between hypothyroidism and the formation of stones in the common bile duct‎.
UR  - https://japer.in/article/the-clinical-picture-of-the-damage-to-the-organs-of-the-hepatobiliopancreatic-area-in-hypothyroidism-6afxgz6igefgiox
ER  -