%0 Journal Article
%T Phytopharmacotherapy of neurodegenerative disorders of the rat brain with an aqueous extract of  Chlorophytum comosum
%A Aida Batrazovna Badrieva
%A Gerontiy Giviyevich Bichenov
%A Zarita Ahmetovna Haluhoeva
%A Aina Ayupovna Arapieva
%A Rasul Musaevitch Baykhanov
%A Zaira Nadirovna Khalibekova
%A Pyatimat Magomedbashirovna Mattcieva
%A Albina Sergeevna Salimova
%J Journal of Advanced Pharmacy Education and Research
%@ 2249-3379
%D 2023
%V 13
%N 3
%R 10.51847/Q0vmEAMGD5
%P 13-18
%X Basic pharmacotherapy of cerebral ischemia includes the use of vasoactive, antiplatelet, nootropic, neuroprotective drugs, antihypoxants, and antioxidants. However, despite their sufficiently high efficiency, their combined use often leads to the development of undesirable reactions. The work aimed to conduct a morphometric study of neurons of the frontal lobe of the brain and the CA1 region of the hippocampus of rats with simulated total ischemia of the brain and correction with an aqueous extract of Chlorophytum comosum. In a statistical study, it was found that ischemic damage to neurons of both the frontal lobe and the hippocampus was significantly more pronounced in the group with a 4-vessel model of brain ischemia without correction with an aqueous extract of Chlorophytum comosum. The minimum diameter, perimeter, and area of neurons, diameter, perimeter, and area of nuclei were significantly different (p
%U https://japer.in/article/phytopharmacotherapy-of-neurodegenerative-disorders-of-the-rat-brain-with-an-aqueous-extract-of-chl-trezbai5bpmg1i6