%0 Journal Article
%T New phytocomplex for chronic obstructive pulmonary disease: Development and clinical evidence of anti-inflammatory effect
%A Evgenia Yurievna Lobach
%A Boisjoni Tokhiriyon
%A Valeriy Mikhailovich Poznyakovsky
%A Sergey Sergeevich Makarov
%A Olga Evgenevna Khanbabayeva
%A Madina Atlaevna Takaeva
%J Journal of Advanced Pharmacy Education and Research
%@ 2249-3379
%D 2023
%V 13
%N 3
%R 10.51847/Tl5LnYDudZ
%P 102-108
%X Chronic diseases of the bronchopulmonary system are common all over the world and the number of working-age population suffering from them is constantly growing. In some cases medications are insufficient, and combination therapy, involving dietary supplements, can be an effective solution. The present paper provides information about a new phytocomplex with active compounds demonstrating synergistic effects. Thirty-five patients diagnosed with chronic obstructive pulmonary disease took part in the clinical trial. Twenty patients (the experimental group) underwent combination therapy, which involved dietary supplement intake alongside medications. Two tablets of the dietary supplement taken daily ensured the supply of rutin – 16 mg, quercetin – 11.2 mg, ascorbic acid – 45 mg, as well as tannins – 24mg. The other fifteen patients (the control group) received the standard treatment. Clinical, instrumental, and laboratory tests were performed to study changes in elastase levels in sputum and blood, blood count, and sputum induction for the participants of both groups before and after the treatment. On Days 3 and 4 promoted sputum expectoration was recorded in the experimental group, and on Day 4 the number of patients with severe cough decreased. The supplement intake did not influence the composition of cellular elements‎.
%U https://japer.in/article/new-phytocomplex-for-chronic-obstructive-pulmonary-disease-development-and-clinical-evidence-of-ant-frsfxfnr51q7bji